Blog

Rexonage³

Blog

Nov 2025

What Does Rexonage³ Actually Do For The Skin? The Science Behind The Buzz

What Does Rexonage³ Actually Do For The Skin? The Science Behind The Buzz

Rexonage³ has become one of the most talked about regenerative treatments in UK aesthetics, particularly among patients looking for natural skin rejuvenation without heat, trauma, or downtime. And with winter on the way, colder weather and central heating often leave the skin feeling tight and dehydrated, making treatments that support cellular repair more relevant than ever.

So, what does Rexonage³ actually do for the skin? And why are patients at Dr Liesel Holler’s Chislehurst clinic turning to this advanced device to strengthen their skin barrier, restore hydration, and improve firmness?

This guide breaks it all down, using accurate science directly from the device’s technology.

Explore Rexonage³ by clicking here.

The Science Of Quantum Molecular Resonance (QMR)

How Rexonage³ Differs From Traditional RF

Rexonage³ uses low intensity, high frequency (4 to 64 MHz) electrical currents through a technology known as Quantum Molecular Resonance (QMR). This is completely different from traditional radiofrequency treatments, which rely on heat to create controlled injury and trigger collagen production.

Instead of heating the tissue, QMR works non thermally, delivering electrical energy at specific high frequencies that resonate at a molecular level. This stimulation supports:

Regeneration of tissue
Improved cellular communication
Activation of repair pathways
Enhanced cell metabolism

Because QMR works without raising skin temperature, it avoids the inflammation and downtime associated with heat-based devices.

This makes Rexonage³ ideal for patients who want regenerative results without any risk of thermal damage, pigmentation issues, or discomfort.

How Rexonage³ Works At the Cellular Level

Collagen And Elastin Regeneration

QMR stimulates fibroblasts – the cells responsible for collagen and elastin production. Over a series of treatments, this helps reinforce the skin’s structure, improving smoothness, firmness, and elasticity.

Skin Tightening Without Heat

While RF or ultrasound tighten the skin through thermal contraction, Rexonage³ supports tightening via cellular regeneration. This means gradual, natural improvement without surface trauma.

Mitochondrial Activation

Research shows QMR enhances mitochondrial activity. This boosts ATP (energy) production, helping cells repair themselves more efficiently.

This can improve:

Hydration
Barrier function
Skin resilience
Recovery from environmental and seasonal stress

Microcirculation Boost

Improved circulation increases nutrient delivery and waste removal, supporting a healthier, more luminous complexion.

Benefits Of Rexonage³ For Common Skin Concerns

Fine Lines And Wrinkles

QMR stimulates new collagen to soften fine lines and support a smoother texture.

Skin Laxity

Improves jawline, lower face, and mid-face firmness with progressive tightening.

Texture, Tone, And Radiance

Enhanced circulation and cell turnover give the skin a fresher, more even appearance.

Barrier Repair After Summer

Ideal post-summer, when UV exposure has weakened the skin. QMR helps restore integrity, hydration, and cellular function as we move into colder months.

Dryness From Winter Weather

As heating turns on and humidity drops, many patients experience dullness and dehydration. QMR helps reinforce the skin’s natural repair systems, making it a great seasonal treatment.

Rexonage³ Compared With Other Regenerative Treatments

Rexonage³ vs RF Microneedling

RF microneedling creates controlled injury + heat.
Rexonage³ delivers regeneration without trauma or heat, suitable even for sensitive skin.

Rexonage³ vs Laser Resurfacing

Lasers remove or heat tissue to stimulate collagen.
QMR supports regeneration without damaging the epidermis, so there is no downtime.

Rexonage³ vs Injectables

Fillers add volume and shape but do not improve skin function.
QMR increases cellular activity, collagen, and hydration for long-term skin health.

What To Expect During Treatment

Number Of Sessions

A course of 6 to 8 sessions, spaced weekly or fortnightly, provides the most noticeable improvement.

Results Timeline

Some patients notice better hydration and glow quickly, but collagen-based improvements build over several months.

 

Is Rexonage³ Right For You?

Downtime

None.
Any mild warmth or pinkness fades quickly.

Ideal For Patients Who Want To:

Improve early or moderate skin laxity
Support long-term skin health
Strengthen barrier function
Reduce fine lines
Boost hydration without injectables
Prepare their skin for winter or recover after summer

Suitability

Most patients aged 30 to 75 are suitable.
Not suitable for those with pacemakers or metal implants in treatment areas.

Where To Get Rexonage³

Dr Liesel Holler offers Rexonage³ at:

Milestones, Royal Parade, Chislehurst, Kent BR6 7NW

Her clinic focuses on regenerative medicine and natural-looking results, making Rexonage³ a perfect fit within her treatment approach.

👉 Ready to explore Rexonage³?
Book your consultation today or sign up to our newsletter for exclusive updates and offers.

 

FAQs

1. Is Rexonage³ safe?

Yes. It is non-thermal, non-invasive, and clinically tested.

2. Does it hurt?

No. Most patients describe a gentle warmth or tingling.

3. How long do results last?

Results last several months and can be maintained with top-up sessions.

4. Can it replace injectables?

No. It improves skin quality, not volume, but it does complement injectable treatments.

5. Can it be used alongside microneedling, PRP, or polynucleotides?

Yes. And it enhances cellular repair, making combination plans effective.

IK H profile pictureIK H
07:30 29 Oct 25
Liesel is professional but friendly and answers all your questions. I would recommend just a consultation, you leave with a wealth of information for you to consider.
Response from the owner 10:25 29 Oct 25
Thank you for such an honest review. We are so happy that you felt so well informed after your consultation, and we hope that this can help to guide you in any treatment choices moving forward.
Michelle Holman profile pictureMichelle Holman
08:13 30 Sep 25
Another visit to Dr Liesel Holler and once again I’m so pleased with the results of my lip filler. The new clinic is lovely and the welcome from reception is great. Highly recommend.
Response from the owner 16:20 18 Dec 23
Thank you Michelle for your great review.. we look forward to seeing you again soon .
Chloe profile pictureChloe
21:31 11 Sep 25
Liesel is amazing! So talented, kind and friendly. I can’t recommend her highly enough!
Response from the owner 10:39 12 Sep 25
Thank you Chloe for this great review. We look forward to seeing you again soon ,at our Chislehurst clinic.
Kerry Hambly profile pictureKerry Hambly
14:29 20 Aug 25
Liesel always takes time making one feel special
She hears what you want to achieve.
Most of all Liesel never hard sells she will not do a procedure if she doesn’t think you will achieve miracles
Response from the owner 15:54 19 Nov 21
Thank you Kerry
Samantha Arnold profile pictureSamantha Arnold
07:19 13 Aug 25
Not one bruise. Lots of discussion on what would be the best option, and all my concerns were listened to and acted upon. Couldn't be happier with the results.
Response from the owner 07:53 18 Aug 25
Thank you for this wonderful review. We are so pleased that you are happy with your experience at our Chislehurst clinic and we look forward to seeing you again.
Virginia Mc dowell profile pictureVirginia Mc dowell
17:17 06 Aug 25
I can’t recommend dr liesel holler enough! She is so caring and professional in he work! She takes a lot of time to really get to know her clients so she can give the best results! I have just had some treatments with her! I am delighted with the result 💇‍♀️❤️
Response from the owner 14:44 07 Jan 21
Thank you Gin! x
priya ilangovan profile picturepriya ilangovan
15:05 20 Jul 25
I had my first and recent Hydra facial here. Agni, was fantastic, friendly, patient and professional throughout the session. I had a very relaxing time and came back home with a healthy facial glow. I would go there again soon for sure for my second session 🤗!
Response from the owner 08:47 21 Jul 25
Thank you Priya for this glowing review. We are thrilled you were so happy with your experience and look forward to welcoming you back to our Chislehurst clinic.
emily profile pictureemily
09:15 12 Jun 25
Dr Liesel Holler is incredibly knowledgable and approachable and I feel I'm in really good hands under her care! She listened to my concerns intently and advised as to the safest way forward.
Response from the owner 09:36 12 Jun 25
Thank you Emily for this review. We are so happy that you feel good under the care of our clinic and Dr Liesel and we look forward to welcoming you back to our Chislehurst clinic in the future.
Ursula Venus profile pictureUrsula Venus
05:58 06 Jun 25
Amazing service from both Shara and Dr Liesel. Very professional
Response from the owner 06:22 06 Jun 25
Thank you so much Ursula for this lovely review. We look forward to seeing you again at our new Chislehurst clinic.
stacey Harwood profile picturestacey Harwood
10:51 24 May 23
Firstly, this is a friendly and welcoming clinic.

Dr Liesel is not only extremely knowledgeable; she also has a genuine care for her patients. She takes the time to listen and what I like best is her approach - less is more! I never feel pushed into anything and she fully explains the procedure and after care. I know I am in safe hands.

A loyal client who is very lucky to find an aesthetic doctor who is professional, smart and caring. Thank you Dr Liesel.
Apples1974 profile pictureApples1974
11:04 26 Apr 23
Dr Holler has a wealth of experience and knowledge that is invaluable. I was nervous ahead of my treatment, but I was immediately put at ease. My procedure was talked through with me thoroughly and Dr Holler took the time to suggest some alternatives that would better suit me. I would absolutely recommend Dr Holler. I couldn't be happier with my results.
Lauren profile pictureLauren
15:26 28 Mar 23
Dr Liesel has a wonderful calming presence about her. You can tell she genuinely cares about each of her patients and will never rush a treatment or go overboard. She takes time to listen to your concerns but is never pushy. She is such a professional and I would recommend her to anyone ☺️
Alexandra Taylor profile pictureAlexandra Taylor
13:41 24 Feb 23
This is my second treatment with Dr Liesel Holler and each time she has discussed and explained things in detail with me and carefully assessed my facial profile.

My results are very natural and exactly as I wanted. It’s clear she is very skilled and knowledgeable and treats each patient uniquely. I can be quite nervous and I feel totally at ease with Dr Liesel Holler and she is the most gentle with a needle that I’ve ever experienced.

I wouldn’t trust anyone else with my face now. Thank you again!