Feb 2023

Learn More About Polynucleotides

Polynucleotides have emerged as a new concept in the field of regenerative bio stimulation for skin rejuvenation. Extracted from salmon DNA, polynucleotides attach to certain receptors of our cells, initiating a cascade of reactions and attracting stem cells to the tissues that are in need of repair or rejuvenation. This leads to an increase in fibroblast and collagen stimulation, giving immediate hydration and a skin tightening effect. After just two weeks, most of the product will have been absorbed, however there will still be fragments of the product left which continues the bio-stimulation.

Polynucleotides are large molecules that make up nucleic acids such as DNA and RNA.

They are composed of nucleotides, which are the building blocks of these molecules.

Polynucleotides promote skin recovery by increasing angiogenesis (new formation of blood vessels), increasing fibroblasts, growth factors and significantly promoting collagen production. These natural gels are composed of high molecular weight polynucleotide chains that possess several unique features that make them highly viscoelastic and capable of binding and orienting a considerable amount of water molecules in space. The synergistic effect of moisturizing, biostimulating, detoxing against free radicals, and contouring/tightening makes polynucleotide-based gels a promising approach for protecting and rejuvenating the skin. The biostimulating effect of polynucleotides leads to the stimulation of type I collagen production and maturation of fibroblasts. The maturation of fibroblasts and the increased production of collagen determine a strong specific lifting and revitalizing effect suitable for all skin types.

The treatment is injected via a cannula or needles and should be repeated once every 15 or 30 days with 2-4 consecutive treatments in total, depending on what the patient wishes to achieve and needs. The results last 6-12 months, depending on age and lifestyle.

In terms of side effects, bruises and some swelling in the injection area for 1-2 days have been reported, but no other side effects have been reported.

It helps decrease fine lines and wrinkles, working as a powerful skin booster to moisturise, reduce free radical damage and boost collagen production.

In summary, the benefits of polynucleotides for skin rejuvenation are manifold. These natural gels have moisturizing, biostimulating, detoxing, and contouring/tightening effects, making them an exciting approach for protecting and rejuvenating skin. With repeated administration over time, polynucleotides recreate the most favourable physiological conditions for fibroblasts’ regeneration and metabolic activity, resulting in long-lasting biorevitalizing effects.

To find out more about the treatment, click here.

Georgina FloraGeorgina Flora
11:40 26 May 23
It was my first time having botox, and understandably was quite nervous about the end result. However Dr Liesel Holler put my mind at ease and explained everything about the procedure, the after care and what to expect. I have waited 3 months to write this review so i could fully see the results. I am so happy with them, they are natural and solved my forehead line/ frown issues.I am just about to go back for a top up! I could not be happier with the results and will continue to return to this lovely clinic!
stacey Harwoodstacey Harwood
10:51 24 May 23
Firstly, this is a friendly and welcoming clinic.Dr Liesel is not only extremely knowledgeable; she also has a genuine care for her patients. She takes the time to listen and what I like best is her approach - less is more! I never feel pushed into anything and she fully explains the procedure and after care. I know I am in safe hands.A loyal client who is very lucky to find an aesthetic doctor who is professional, smart and caring. Thank you Dr Liesel.
11:04 26 Apr 23
Dr Holler has a wealth of experience and knowledge that is invaluable. I was nervous ahead of my treatment, but I was immediately put at ease. My procedure was talked through with me thoroughly and Dr Holler took the time to suggest some alternatives that would better suit me. I would absolutely recommend Dr Holler. I couldn't be happier with my results.
15:26 28 Mar 23
Dr Liesel has a wonderful calming presence about her. You can tell she genuinely cares about each of her patients and will never rush a treatment or go overboard. She takes time to listen to your concerns but is never pushy. She is such a professional and I would recommend her to anyone ☺️
Alexandra TaylorAlexandra Taylor
13:41 24 Feb 23
This is my second treatment with Dr Liesel Holler and each time she has discussed and explained things in detail with me and carefully assessed my facial profile.My results are very natural and exactly as I wanted. It’s clear she is very skilled and knowledgeable and treats each patient uniquely. I can be quite nervous and I feel totally at ease with Dr Liesel Holler and she is the most gentle with a needle that I’ve ever experienced.I wouldn’t trust anyone else with my face now. Thank you again!