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Feb 2026

Nuchido TIME+ Now Stocked at Dr Liesel Holler – A Next Generation NAD+ Approach to Ageing Well

What if ageing is less about wrinkles and more about what is happening inside your cells?

Long before changes appear on the surface, NAD+ levels begin to decline. As this vital molecule drops, cellular energy slows, inflammation increases, and the body’s ability to repair itself becomes less efficient. The result? Fatigue that lingers. Slower recovery. Skin that looks duller despite good skincare.

At Dr Liesel Holler Medical Aesthetics, we approach ageing differently. We look beneath the surface. That is why we are now stocking Nuchido TIME+.

This next generation NAD+ booster supplement is designed to restore the body’s natural NAD+ production by addressing the root causes of its decline. It does not contain NAD+ itself. Instead, it supports sustainable cellular repair and inflammation regulation from within.

If you are searching for a trusted NAD+ supplement UK, exploring how to increase NAD+ naturally, or seeking medically guided support for fatigue, menopause symptoms or post treatment recovery, this is where science-led regenerative care begins.

What Is NAD+ and Why Does It Decline As We Age?

The Role of NAD+ in Cellular Energy and Repair

NAD+ is a molecule found in every cell of the body. It plays a central role in mitochondrial function, DNA repair pathways and the activation of sirtuins, which regulate cellular ageing.

In simple terms, NAD+ powers cellular energy production and supports the maintenance and repair systems that keep cells functioning efficiently. When NAD+ levels are adequate, cells repair damage more effectively and inflammation remains controlled.

How NAD+ Decline Contributes to Fatigue, Skin Ageing and Inflammation

Research suggests NAD+ levels can decline by up to 50 per cent every 20 years. Lifestyle factors such as stress, poor sleep, metabolic imbalance and environmental exposure accelerate this decline.

Reduced NAD+ is associated with:

  • Increased systemic inflammation
  • Oxidative stress
  • Slower skin cell turnover
  • Reduced collagen support
  • Brain fog
  • Lower endurance
  • Poor recovery

For patients undergoing regenerative aesthetic treatments, optimal cellular health is not optional. It is foundational. This is where targeted NAD+ support becomes clinically relevant.

What Makes Nuchido TIME+ Different From Other NAD+ Supplements?

The market for NAD+ supplements is growing rapidly. However, not all products work in the same way.

Why Nuchido TIME+ Does Not Contain NAD+

Nuchido TIME+ is formulated to stimulate the body’s own production of NAD+ and reduce inflammation within the cell. Rather than supplying NAD+ directly, it addresses the biological mechanisms behind NAD+ depletion.

This is important. Simply introducing NAD+ into the bloodstream does not necessarily correct the underlying dysfunction contributing to its decline.

Nuchido TIME+ vs NMN, NR and NAD+ IV Therapy

Feature Nuchido TIME+ wNMN / NR NAD+ IV Therapy
Targets root causes of NAD+ decline Yes No No
Human clinical trials Yes Variable Limited
Whole system approach Yes No No
Boosts cellular NAD+, not just blood levels Yes Limited Short term

 

If you are searching for NAD+ supplement vs IV therapy or wondering is Nuchido TIME+ better than NMN, the key difference lies in the mechanism. Nuchido TIME+ is designed as a whole-body cellular support supplement.

Clinical Evidence Behind Nuchido TIME+

Nuchido TIME+ has been tested in human clinical trials. Results indicate increased cellular NAD+ levels within seven days in study participants.

Reported benefits include:

  • Boosted NAD+
  • Reduced inflammation
  • Improved energy levels
  • Improved sleep quality
  • Reduced brain fog
  • Enhanced recovery
  • Improved skin health

From a clinical perspective, this is significant. Inflammation reduction and mitochondrial support are central to longevity medicine and regenerative aesthetics.

We are selective about what we stock. Products must align with a medically driven philosophy grounded in evidence and patient safety.

Whole-Body Benefits of Nuchido TIME+

Increased Energy Levels

Mitochondrial function improves when NAD+ is supported. Patients often report improved endurance and reduced afternoon fatigue.

Improved Sleep Quality

Sleep is closely linked to cellular repair. Supporting NAD+ may enhance sleep architecture and recovery capacity.

Reduced Brain Fog

Cognitive clarity is frequently linked to metabolic health. Supporting cellular energy pathways can positively influence mental sharpness.

Improved Skin Health

Cellular regeneration underpins skin quality. NAD+ plays a role in DNA repair and inflammation control, both of which influence collagen stability and skin integrity.

For patients undergoing improving skin quality at a cellular level, this internal support complements in-clinic procedures.

Improved Recovery Post Treatment

Patients investing in advanced cellular regeneration treatments such as exosomes, microneedling or laser resurfacing may benefit from enhanced systemic support.

If you are exploring regenerative aesthetic treatments, internal optimisation can enhance external outcomes.

Who Is Nuchido TIME+ Suitable For?

Patients Experiencing Fatigue or Brain Fog

Low energy and mental sluggishness are common complaints in patients over 35. Supporting NAD+ may improve resilience.

Menopause Support and Hormonal Transition

Hormonal changes influence mitochondrial efficiency and inflammation. Patients searching for NAD+ support for menopause symptoms may benefit from a consultation to determine suitability.

Pre and Post Aesthetic Treatment Recovery

Patients undergoing microneedling, regenerative injectables or laser therapy often ask how to optimise recovery. Internal support may enhance repair mechanisms.

Patients Focused on Longevity and Preventative Ageing

If you are interested in biological age versus chronological age, NAD+ support may form part of a broader longevity strategy.

Safety and Contraindications

Nuchido TIME+ is:

  • Vegan
  • Gluten free
  • Non GMO
  • Compliant with UK and EU food supplement regulations

It is not recommended for:

  • Individuals with active cancer
  • Those undergoing cancer treatment
  • Pregnant or breastfeeding women

Patients taking prescription medication should consult a medical professional before starting any supplement.

How To Take Nuchido TIME+

The recommended dosage is three capsules twice a day with food and water.

While some individuals report benefits within one week, outcomes vary depending on age, health status and metabolic function.

Patients are encouraged to track objective markers such as:

  • Sleep quality
  • HRV
  • Exercise recovery
  • Energy levels

If you are searching how long does NAD+ supplement take to work, a personalised consultation provides clarity.

Why We Stock Nuchido TIME+ at Dr Liesel Holler

At Dr Liesel Holler Medical Aesthetics, we do not follow trends. We follow science.

Our clinic philosophy centres on consultation-led, medically driven care. We understand that injectable treatments, laser procedures and regenerative therapies achieve optimal results when the body’s cellular environment is supported.

Stocking Nuchido TIME+ reflects our commitment to whole-body ageing well. It aligns with our approach to cellular support for hair health, skin rejuvenation and preventative medicine.

If you are searching for where to buy Nuchido TIME+ in Kent or Nuchido TIME+ Chislehurst clinic, we welcome you to book a consultation.

To discuss suitability or to book a consultation, contact our team today.

Frequently Asked Questions

What is Nuchido TIME+?

A clinically tested NAD+ booster supplement designed to restore natural NAD+ production and reduce cellular inflammation.

Is Nuchido TIME+ better than NMN?

It works differently. Rather than supplying precursors alone, it addresses root causes of NAD+ decline.

How long does it take to see results?

Some individuals notice changes within one week. Others experience gradual improvement over several weeks.

Is Nuchido TIME+ safe?

It complies with UK and EU supplement regulations. Suitability should always be assessed individually.

Can I take Nuchido TIME+ with HRT?

It may be taken alongside other supplements, but medical advice is recommended.

IK H profile pictureIK H
07:30 29 Oct 25
Liesel is professional but friendly and answers all your questions. I would recommend just a consultation, you leave with a wealth of information for you to consider.
Response from the owner 10:25 29 Oct 25
Thank you for such an honest review. We are so happy that you felt so well informed after your consultation, and we hope that this can help to guide you in any treatment choices moving forward.
Michelle Holman profile pictureMichelle Holman
08:13 30 Sep 25
Another visit to Dr Liesel Holler and once again I’m so pleased with the results of my lip filler. The new clinic is lovely and the welcome from reception is great. Highly recommend.
Response from the owner 16:20 18 Dec 23
Thank you Michelle for your great review.. we look forward to seeing you again soon .
Chloe profile pictureChloe
21:31 11 Sep 25
Liesel is amazing! So talented, kind and friendly. I can’t recommend her highly enough!
Response from the owner 10:39 12 Sep 25
Thank you Chloe for this great review. We look forward to seeing you again soon ,at our Chislehurst clinic.
Kerry Hambly profile pictureKerry Hambly
14:29 20 Aug 25
Liesel always takes time making one feel special
She hears what you want to achieve.
Most of all Liesel never hard sells she will not do a procedure if she doesn’t think you will achieve miracles
Response from the owner 15:54 19 Nov 21
Thank you Kerry
Samantha Arnold profile pictureSamantha Arnold
07:19 13 Aug 25
Not one bruise. Lots of discussion on what would be the best option, and all my concerns were listened to and acted upon. Couldn't be happier with the results.
Response from the owner 07:53 18 Aug 25
Thank you for this wonderful review. We are so pleased that you are happy with your experience at our Chislehurst clinic and we look forward to seeing you again.
Virginia Mc dowell profile pictureVirginia Mc dowell
17:17 06 Aug 25
I can’t recommend dr liesel holler enough! She is so caring and professional in he work! She takes a lot of time to really get to know her clients so she can give the best results! I have just had some treatments with her! I am delighted with the result 💇‍♀️❤️
Response from the owner 14:44 07 Jan 21
Thank you Gin! x
priya ilangovan profile picturepriya ilangovan
15:05 20 Jul 25
I had my first and recent Hydra facial here. Agni, was fantastic, friendly, patient and professional throughout the session. I had a very relaxing time and came back home with a healthy facial glow. I would go there again soon for sure for my second session 🤗!
Response from the owner 08:47 21 Jul 25
Thank you Priya for this glowing review. We are thrilled you were so happy with your experience and look forward to welcoming you back to our Chislehurst clinic.
emily profile pictureemily
09:15 12 Jun 25
Dr Liesel Holler is incredibly knowledgable and approachable and I feel I'm in really good hands under her care! She listened to my concerns intently and advised as to the safest way forward.
Response from the owner 09:36 12 Jun 25
Thank you Emily for this review. We are so happy that you feel good under the care of our clinic and Dr Liesel and we look forward to welcoming you back to our Chislehurst clinic in the future.
Ursula Venus profile pictureUrsula Venus
05:58 06 Jun 25
Amazing service from both Shara and Dr Liesel. Very professional
Response from the owner 06:22 06 Jun 25
Thank you so much Ursula for this lovely review. We look forward to seeing you again at our new Chislehurst clinic.
stacey Harwood profile picturestacey Harwood
10:51 24 May 23
Firstly, this is a friendly and welcoming clinic.

Dr Liesel is not only extremely knowledgeable; she also has a genuine care for her patients. She takes the time to listen and what I like best is her approach - less is more! I never feel pushed into anything and she fully explains the procedure and after care. I know I am in safe hands.

A loyal client who is very lucky to find an aesthetic doctor who is professional, smart and caring. Thank you Dr Liesel.
Apples1974 profile pictureApples1974
11:04 26 Apr 23
Dr Holler has a wealth of experience and knowledge that is invaluable. I was nervous ahead of my treatment, but I was immediately put at ease. My procedure was talked through with me thoroughly and Dr Holler took the time to suggest some alternatives that would better suit me. I would absolutely recommend Dr Holler. I couldn't be happier with my results.
Lauren profile pictureLauren
15:26 28 Mar 23
Dr Liesel has a wonderful calming presence about her. You can tell she genuinely cares about each of her patients and will never rush a treatment or go overboard. She takes time to listen to your concerns but is never pushy. She is such a professional and I would recommend her to anyone ☺️
Alexandra Taylor profile pictureAlexandra Taylor
13:41 24 Feb 23
This is my second treatment with Dr Liesel Holler and each time she has discussed and explained things in detail with me and carefully assessed my facial profile.

My results are very natural and exactly as I wanted. It’s clear she is very skilled and knowledgeable and treats each patient uniquely. I can be quite nervous and I feel totally at ease with Dr Liesel Holler and she is the most gentle with a needle that I’ve ever experienced.

I wouldn’t trust anyone else with my face now. Thank you again!