Cosmelan® is a globally recognised depigmentation treatment designed to address stubborn pigmentation at its source. It is a professional, non-invasive system that uses a targeted biochemical approach to regulate melanin production and restore clearer, more even skin without heat, needles or energy-based devices.
Unlike resurfacing treatments that rely on controlled injury, Cosmelan® works through a precise combination of tyrosinase-inhibiting ingredients that interrupt excess pigment formation within the melanocytes. This intervention at a molecular level reduces existing pigmentation while helping to prevent future recurrence.
Cosmelan® is especially effective for complex or hormonally driven pigmentation such as melasma, sun-induced pigmentation, and post-inflammatory hyperpigmentation. By regulating the biological pathways behind melanogenesis, it supports natural skin renewal and long-term brightness without the downtime associated with lasers or heat-based therapies.
Cosmelan® is a professional depigmentation treatment that targets pigmentation at its origin within the melanocytes. Rather than relying on heat, injury or abrasion, it uses a precise combination of ingredients to regulate melanin production and correct visible discolouration. This biochemical approach allows Cosmelan® to treat complex pigmentation conditions safely and effectively, restoring clarity and balance to the skin.
If you’re seeking a clinically proven, medical solution for stubborn pigmentation, uneven tone or melasma, Cosmelan® offers a targeted depigmentation approach led by Dr Liesel Holler. As an internationally trained cosmetic doctor, she will analyse your skin in detail and design a structured protocol that supports clearer, brighter and more balanced skin.
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Chislehurst, Bromley
Cosmelan is a professional depigmentation peel that targets melasma and stubborn dark patches. It is applied as a mask in clinic and left on for a prescribed period of time. The second part of the treatment is applied at home.
Not really, you can expect warmth and tingling under the mask, then some redness and peeling after. It’s more intense than painful.
Clinic time is about 30 mins. The mask stays on for 6-12 hrs. Peeling lasts up to 10 days.
With strict SPF and your homecare routine, results can last years.
Yes – and this is one of the reasons Cosmelan® is widely recommended for stubborn pigmentation. It can be safely used on sensitive facial zones, including areas affected by melasma or post-inflammatory pigmentation, without the risks linked to thermal or energy-based treatments.
Most patients undergo one full Cosmelan® programme, which includes the in-clinic mask followed by the structured home protocol. Improvements begin within the first few weeks, with clarity and brightness developing progressively. A personalised plan ensures the treatment is matched to your specific type of pigmentation.
Yes. The in-clinic application is straightforward, and although you may feel warmth or tingling as the actives take effect, the process is well tolerated. The home phase may involve peeling and redness, which are expected signs of the depigmentation process working.
