PRP Filler

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PRP Filler (Biofiller with Plasma Gel)

Available exclusively at our Chislehurst clinic

PRP filler, also known as PRP DermalFiller or Biofiller with Plasma Gel, is a regenerative treatment that volumises, smooths, and revitalises the skin using only your own blood. No synthetic fillers. No hyaluronic acid. Just your body’s natural healing power, carefully concentrated, activated, and reinjected to deliver subtle volume and better skin quality.

It’s an ideal option for patients seeking a holistic alternative to traditional dermal fillers or for those with sensitivities to conventional ingredients.

How It Works

This is not a hybrid filler. There’s no hyaluronic acid involved at any point. Instead, we process a sample of your own blood to separate the platelet-rich plasma (PRP). Part of this plasma is heated to form a soft gel. Once cooled, it’s combined with the remaining liquid PRP to create a smooth, gel-like filler with the right consistency for injection.

This gel mimics the texture of natural fat, allowing it to gently restore volume while delivering the regenerative benefits of PRP, such as improved skin tone, texture, and elasticity from the growth factors within your own platelets.

What It Can Treat

  •  Loss of facial volume
  • Fine lines and wrinkles
  • Under-eye hollows
  • Cheek contour
  • Neck lines
  • Ageing hands
  • Acne scarring or recessed marks

What Makes It Different

Unlike conventional fillers, PRP filler is completely biocompatible because it’s made from you. There’s no risk of allergic reaction or rejection. It’s especially suitable for those seeking natural-looking results and a gradual, regenerative effect.

As it integrates with your own tissue, it not only adds soft volume but stimulates collagen production over time. This gives a fresher, firmer appearance that evolves over several weeks.

Procedure

PRP (Platelet-Rich Plasma) filler treatment begins by drawing a small amount of your blood, which is then spun in a centrifuge to separate the platelet-rich plasma. This plasma, rich in growth factors, is then carefully injected into targeted areas of the face using fine needles or cannulas. It’s often combined with a dermal filler or bio-filler for added volume and support, delivering both immediate contouring and long-term regenerative benefits. The entire procedure typically takes around 45-60 minutes.

Is It Painful?

Most patients find the procedure comfortable and well-tolerated. A topical numbing cream is applied beforehand to minimise any discomfort during the injections. You may feel a mild stinging or pressure sensation during the treatment, but it’s generally described as manageable. There is little to no downtime, although some redness, swelling, or bruising may occur temporarily.

How Long Does It Take?

The full process takes around 90 to 120 minutes. This includes consultation, blood draw, processing the plasma into gel, and careful injection using advanced techniques.

What Are The Results Like?

You may notice soft volume immediately post-treatment due to the structure of the plasma gel itself. Skin improvements, like smoother texture, better tone, and firmer contours, build gradually over 2 to 12 weeks as your natural collagen response kicks in.

Popular questions

How Long Do Results Last?

Expect results to last approximately 8 months after completing the recommended course of two sessions, spaced 8 weeks apart. Maintenance sessions can be planned annually or biannually, depending on your skin’s needs.

How Do PRP Fillers Work?

PRP Fillers are a 100% natural injectable treatment made from your own blood. After drawing a small amount of blood, it’s spun in a centrifuge to separate the platelet-rich plasma. This golden plasma is then reinjected into areas of concern, acting as a natural biostimulatory filler that supports collagen production, improves skin tone, and restores volume in a subtle, regenerative way.

What Are the Clinical Benefits and Applications?

PRP Fillers are ideal for treating:

  • Hollow or sunken under-eyes (tear troughs)
  • Fine lines around the mouth, temples, and midface
  • Skin that appears dull, dehydrated, or thinning
  • Early signs of volume loss with skin laxity
  • They are especially well-suited for patients seeking a holistic alternative to synthetic fillers, with long-term skin quality improvement.

Are the Results Backed by Research?

Yes. PRP has been extensively studied in regenerative medicine and aesthetics. It has been shown to stimulate fibroblasts, boost collagen production, and improve vascular supply to the skin. Clinical research supports its use in treating volume loss, dark circles, and crepey skin, especially in delicate areas where traditional fillers may not be advised.

IK H profile pictureIK H
07:30 29 Oct 25
Liesel is professional but friendly and answers all your questions. I would recommend just a consultation, you leave with a wealth of information for you to consider.
Response from the owner 10:25 29 Oct 25
Thank you for such an honest review. We are so happy that you felt so well informed after your consultation, and we hope that this can help to guide you in any treatment choices moving forward.
Michelle Holman profile pictureMichelle Holman
08:13 30 Sep 25
Another visit to Dr Liesel Holler and once again I’m so pleased with the results of my lip filler. The new clinic is lovely and the welcome from reception is great. Highly recommend.
Response from the owner 16:20 18 Dec 23
Thank you Michelle for your great review.. we look forward to seeing you again soon .
Chloe profile pictureChloe
21:31 11 Sep 25
Liesel is amazing! So talented, kind and friendly. I can’t recommend her highly enough!
Response from the owner 10:39 12 Sep 25
Thank you Chloe for this great review. We look forward to seeing you again soon ,at our Chislehurst clinic.
Kerry Hambly profile pictureKerry Hambly
14:29 20 Aug 25
Liesel always takes time making one feel special
She hears what you want to achieve.
Most of all Liesel never hard sells she will not do a procedure if she doesn’t think you will achieve miracles
Response from the owner 15:54 19 Nov 21
Thank you Kerry
Samantha Arnold profile pictureSamantha Arnold
07:19 13 Aug 25
Not one bruise. Lots of discussion on what would be the best option, and all my concerns were listened to and acted upon. Couldn't be happier with the results.
Response from the owner 07:53 18 Aug 25
Thank you for this wonderful review. We are so pleased that you are happy with your experience at our Chislehurst clinic and we look forward to seeing you again.
Virginia Mc dowell profile pictureVirginia Mc dowell
17:17 06 Aug 25
I can’t recommend dr liesel holler enough! She is so caring and professional in he work! She takes a lot of time to really get to know her clients so she can give the best results! I have just had some treatments with her! I am delighted with the result 💇‍♀️❤️
Response from the owner 14:44 07 Jan 21
Thank you Gin! x
priya ilangovan profile picturepriya ilangovan
15:05 20 Jul 25
I had my first and recent Hydra facial here. Agni, was fantastic, friendly, patient and professional throughout the session. I had a very relaxing time and came back home with a healthy facial glow. I would go there again soon for sure for my second session 🤗!
Response from the owner 08:47 21 Jul 25
Thank you Priya for this glowing review. We are thrilled you were so happy with your experience and look forward to welcoming you back to our Chislehurst clinic.
emily profile pictureemily
09:15 12 Jun 25
Dr Liesel Holler is incredibly knowledgable and approachable and I feel I'm in really good hands under her care! She listened to my concerns intently and advised as to the safest way forward.
Response from the owner 09:36 12 Jun 25
Thank you Emily for this review. We are so happy that you feel good under the care of our clinic and Dr Liesel and we look forward to welcoming you back to our Chislehurst clinic in the future.
Ursula Venus profile pictureUrsula Venus
05:58 06 Jun 25
Amazing service from both Shara and Dr Liesel. Very professional
Response from the owner 06:22 06 Jun 25
Thank you so much Ursula for this lovely review. We look forward to seeing you again at our new Chislehurst clinic.
stacey Harwood profile picturestacey Harwood
10:51 24 May 23
Firstly, this is a friendly and welcoming clinic.

Dr Liesel is not only extremely knowledgeable; she also has a genuine care for her patients. She takes the time to listen and what I like best is her approach - less is more! I never feel pushed into anything and she fully explains the procedure and after care. I know I am in safe hands.

A loyal client who is very lucky to find an aesthetic doctor who is professional, smart and caring. Thank you Dr Liesel.
Apples1974 profile pictureApples1974
11:04 26 Apr 23
Dr Holler has a wealth of experience and knowledge that is invaluable. I was nervous ahead of my treatment, but I was immediately put at ease. My procedure was talked through with me thoroughly and Dr Holler took the time to suggest some alternatives that would better suit me. I would absolutely recommend Dr Holler. I couldn't be happier with my results.
Lauren profile pictureLauren
15:26 28 Mar 23
Dr Liesel has a wonderful calming presence about her. You can tell she genuinely cares about each of her patients and will never rush a treatment or go overboard. She takes time to listen to your concerns but is never pushy. She is such a professional and I would recommend her to anyone ☺️
Alexandra Taylor profile pictureAlexandra Taylor
13:41 24 Feb 23
This is my second treatment with Dr Liesel Holler and each time she has discussed and explained things in detail with me and carefully assessed my facial profile.

My results are very natural and exactly as I wanted. It’s clear she is very skilled and knowledgeable and treats each patient uniquely. I can be quite nervous and I feel totally at ease with Dr Liesel Holler and she is the most gentle with a needle that I’ve ever experienced.

I wouldn’t trust anyone else with my face now. Thank you again!